Basic and Clinical Andrology (Mar 2023)

Homocysteine levels correlate with AVSS-RigiScan test parameters in men with erectile dysfunction

  • Xin Qian,
  • Xing Tao,
  • Yangyang Gong,
  • Can Ran,
  • Yougang Feng,
  • Hongjian Liu

DOI
https://doi.org/10.1186/s12610-022-00181-9
Journal volume & issue
Vol. 33, no. 1
pp. 1 – 7

Abstract

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Abstract Background Although elevated homocysteine levels have been shown to affect penile erection, the relationship between homocysteine and erection at the tip or base of the penis has not been extensively studied. Results We found that homocysteine levels were negatively correlated with the average event rigidity of the base (r = -0.2225, p = 0.0142). Homocysteine levels were also negatively correlated with the average maximum rigidity of the base (r = -0.2164, p = 0.0171). In particular, homocysteine levels were negatively correlated with ∆ Tumescence of the tip (r = -0.1866, p = 0.0404). Similarly, homocysteine was negatively correlated with ∆ Tumescence of the base (r = -0.2257, p = 0.0128). Conclusion Our data showed that homocysteine inhibits penile erection. At the same time, homocysteine levels were negatively correlated with the parameters of the AVSS-RigiScan test.

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