Clinical Case Reports (Apr 2022)

Improvement of depression in a patient with hypothyroidism and deiodinase polymorphism with LT3 Therapy

  • Ziyan S. Ahmed,
  • Rinsha P. V. Sherin,
  • Tatiana L. Fonseca,
  • Thanh D. Hoang,
  • Mohamed K. M. Shakir

DOI
https://doi.org/10.1002/ccr3.5651
Journal volume & issue
Vol. 10, no. 4
pp. n/a – n/a

Abstract

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Abstract We report a 54‐year‐old man with treatment‐resistant depression (TRD) and hypothyroidism who responded to LT3/LT4 combination, rather than LT4 alone. He was able to discontinue all antidepressant medications eventually. Interestingly, the patient has a DIO2 polymorphism.

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