Nature Communications (Apr 2020)
Integrative multiplatform molecular profiling of benign prostatic hyperplasia identifies distinct subtypes
- Deli Liu,
- Jonathan E. Shoag,
- Daniel Poliak,
- Ramy S. Goueli,
- Vaishali Ravikumar,
- David Redmond,
- Aram Vosoughi,
- Jacqueline Fontugne,
- Heng Pan,
- Daniel Lee,
- Domonique Thomas,
- Keyan Salari,
- Zongwei Wang,
- Alessandro Romanel,
- Alexis Te,
- Richard Lee,
- Bilal Chughtai,
- Aria F. Olumi,
- Juan Miguel Mosquera,
- Francesca Demichelis,
- Olivier Elemento,
- Mark A. Rubin,
- Andrea Sboner,
- Christopher E. Barbieri
Affiliations
- Deli Liu
- Sandra and Edward Meyer Cancer Center, Weill Cornell Medicine
- Jonathan E. Shoag
- Sandra and Edward Meyer Cancer Center, Weill Cornell Medicine
- Daniel Poliak
- Department of Radiology, Weill Cornell Medicine
- Ramy S. Goueli
- Department of Urology, Weill Cornell Medicine
- Vaishali Ravikumar
- Department of Urology, Weill Cornell Medicine
- David Redmond
- Department of Medicine, Weill Cornell Medicine
- Aram Vosoughi
- Department of Pathology and Laboratory Medicine, Weill Cornell Medical College
- Jacqueline Fontugne
- Englander Institute for Precision Medicine of Weill Cornell Medicine and NewYork-Presbyterian Hospital
- Heng Pan
- Englander Institute for Precision Medicine of Weill Cornell Medicine and NewYork-Presbyterian Hospital
- Daniel Lee
- Department of Urology, Weill Cornell Medicine
- Domonique Thomas
- Department of Urology, Weill Cornell Medicine
- Keyan Salari
- Department of Urology, Massachusetts General Hospital, Harvard Medical School
- Zongwei Wang
- Beth Israel Deaconess Medical Center, Harvard Medical School
- Alessandro Romanel
- Department of Cellular, Computational and Integrative Biology (CIBIO)
- Alexis Te
- Department of Urology, Weill Cornell Medicine
- Richard Lee
- Department of Urology, Weill Cornell Medicine
- Bilal Chughtai
- Department of Urology, Weill Cornell Medicine
- Aria F. Olumi
- Beth Israel Deaconess Medical Center, Harvard Medical School
- Juan Miguel Mosquera
- HRH Prince Alwaleed Bin Talal Bin Abdulaziz Alsaud Institute for Computational Biomedicine, Weill Cornell Medical College
- Francesca Demichelis
- Department of Cellular, Computational and Integrative Biology (CIBIO)
- Olivier Elemento
- HRH Prince Alwaleed Bin Talal Bin Abdulaziz Alsaud Institute for Computational Biomedicine, Weill Cornell Medical College
- Mark A. Rubin
- Englander Institute for Precision Medicine of Weill Cornell Medicine and NewYork-Presbyterian Hospital
- Andrea Sboner
- Sandra and Edward Meyer Cancer Center, Weill Cornell Medicine
- Christopher E. Barbieri
- Sandra and Edward Meyer Cancer Center, Weill Cornell Medicine
- DOI
- https://doi.org/10.1038/s41467-020-15913-6
- Journal volume & issue
-
Vol. 11,
no. 1
pp. 1 – 9
Abstract
Benign prostatic hyperplasia (BPH) is one of the most common diseases affecting aging men with limited therapeutic options. In this study, the authors describe the molecular characterization of BPH performing genomic, transcriptomic and epigenetic analysis of 18 BPH cases.
