Control of human cytomegalovirus replication by liver resident natural killer cells

Calum Forrest; Thomas J. G. Chase; Antonia O. Cuff; Dionas Maroulis; Reza Motallebzadeh; Amir Gander; Brian Davidson; Paul Griffiths; Victoria Male; Matthew Reeves

doi:10.1038/s41467-023-37181-w

Nature Communications (Mar 2023)

Control of human cytomegalovirus replication by liver resident natural killer cells

Calum Forrest,
Thomas J. G. Chase,
Antonia O. Cuff,
Dionas Maroulis,
Reza Motallebzadeh,
Amir Gander,
Brian Davidson,
Paul Griffiths,
Victoria Male,
Matthew Reeves

Affiliations

Calum Forrest: Institute of Immunity & Transplantation, UCL
Thomas J. G. Chase: Department of Surgery, UCL, Royal Free Campus
Antonia O. Cuff: Department of Metabolism, Digestion and Reproduction, Imperial College London, Chelsea & Westminster Campus
Dionas Maroulis: Department of Surgery, UCL, Royal Free Campus
Reza Motallebzadeh: Department of Surgery, UCL, Royal Free Campus
Amir Gander: Department of Surgery, UCL, Royal Free Campus
Brian Davidson: Department of Surgery, UCL, Royal Free Campus
Paul Griffiths: Institute of Immunity & Transplantation, UCL
Victoria Male: Department of Metabolism, Digestion and Reproduction, Imperial College London, Chelsea & Westminster Campus
Matthew Reeves: Institute of Immunity & Transplantation, UCL

DOI: https://doi.org/10.1038/s41467-023-37181-w
Journal volume & issue: Vol. 14, no. 1
pp. 1 – 10

Abstract

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Natural killer cells play important roles in the immune response to human cytomegalovirus infection. Here the authors implicate donor-derived liver resident natural killer cells in the control of human cytomegalovirus infection by analysis of perfusates derived from human transplant livers.

Published in Nature Communications

ISSN: 2041-1723 (Online)
Publisher: Nature Portfolio
Country of publisher: United Kingdom
LCC subjects: Science
Website: https://www.nature.com/ncomms/

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