Nature Communications (Mar 2020)

Gene clustering and copy number variation in alkaloid metabolic pathways of opium poppy

  • Qiushi Li,
  • Sukanya Ramasamy,
  • Pooja Singh,
  • Jillian M. Hagel,
  • Sonja M. Dunemann,
  • Xue Chen,
  • Rongji Chen,
  • Lisa Yu,
  • Joseph E. Tucker,
  • Peter J. Facchini,
  • Sam Yeaman

DOI
https://doi.org/10.1038/s41467-020-15040-2
Journal volume & issue
Vol. 11, no. 1
pp. 1 – 13

Abstract

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The opium poppy has been a source of painkilling drugs synthesized by the benzylisoquinoline alkaloid pathway. Here, the authors report an improved genome assembly and reveal gene clustering and copy number variation in alkaloid metabolic pathways.