A Drosophila chemical screen reveals synergistic effect of MEK and DGKα inhibition in Ras-driven cancer

• John E. La Marca,
• Robert W. Ely,
• Sarah T. Diepstraten,
• Peter Burke,
• Gemma L. Kelly,
• Patrick O. Humbert,
• Helena E. Richardson

Affiliations

John E. La Marca

Department of Biochemistry & Chemistry, La Trobe Institute for Molecular Science, La Trobe University, Bundoora, Victoria 3086, Australia

Robert W. Ely

Department of Biochemistry & Chemistry, La Trobe Institute for Molecular Science, La Trobe University, Bundoora, Victoria 3086, Australia

Sarah T. Diepstraten

Blood Cells and Blood Cancer Division, Water and Eliza Hall Institute, Melbourne, Victoria 3052, Australia

Peter Burke

Department of Biochemistry & Chemistry, La Trobe Institute for Molecular Science, La Trobe University, Bundoora, Victoria 3086, Australia

Gemma L. Kelly

Blood Cells and Blood Cancer Division, Water and Eliza Hall Institute, Melbourne, Victoria 3052, Australia

Patrick O. Humbert

Department of Biochemistry & Chemistry, La Trobe Institute for Molecular Science, La Trobe University, Bundoora, Victoria 3086, Australia

Helena E. Richardson

Department of Biochemistry & Chemistry, La Trobe Institute for Molecular Science, La Trobe University, Bundoora, Victoria 3086, Australia