Radiation therapy in treatment of Rosai–Dorfman disease: literature review and report of a patient with cutaneous form

Abstract

RosaiDorfman disease (RDD) is a rare variant of the nonlangergans histiocytosis. Various presentation, systemic and localised forms and limited publications make diagnostics and prompt management difficult. Aim. Literature review and presentation of the patient with cutaneous form of RDD. Results. The patient is a 56 y.o male. In October 2019 he noticed a tumour in the left temporal area. After 3 weeks the tumor was removed. During the next two weeks the tumour recurred within the post-operative scar. After the review of the specimen and staging the skin form RosaiDorfman disease was diagnosed. Irradiation (total dose 36 Gr) was conducted. The tumor lessened. Through the next 4 months response is stable. Сonclusion. Radiation therapy as a second line of treatment of the skin RDD led to a stable response.

Keywords

• rosai–dorfman disease
• irradiation
• histiocytosis
• emperiopolesis