Plastic and Reconstructive Surgery, Global Open (Jun 2022)

Successful Treatment of Wound Dehiscence by Innovative Type 1 Collagen Flowable Gel: A Case Report

  • Giuseppe A. Ferraro, MD, PhD,
  • Giuseppe Lanzano, MD,
  • Elisa Grella, MD, PhD,
  • Adelmo Gubitosi, MD, PhD,
  • Giovanni F. Nicoletti, MD, PhD

DOI
https://doi.org/10.1097/GOX.0000000000004360
Journal volume & issue
Vol. 10, no. 6
p. e4360

Abstract

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Summary:. The growing demand for postbariatric body-contouring surgery after massive weight loss goes hand-in-hand with an increase in wound complications. Consequently, surgical reoperation or conservative management is necessary and represents a difficult challenge to healthcare professionals. Moreover, it is well known that postbariatric patients present aberrant wound healing due to multifactorial causes, such as preoperative illness, nutritional deficiencies, and vascular disease. To treat such complex wounds, several methods have been recommended, such as the use of negative pressure wound therapy, tissue-engineered skin substitutes, and collagen-based wound dressings. The case presented here is of a patient with deep wound dehiscence of the inner left thigh, 1 week after a medial thigh lift procedure, successfully managed with Vergenix Flowable Gel, a human recombinant type I collagen produced in plants. After 2 weeks of treatment, wound dehiscence was replaced with granulation tissue, and after 4 weeks, the patient was completely healed, with an acceptable aesthetic outcome of the surgical scar.