Prognostic Value of the Ratio of Hemoglobin to Red Blood Cell Distribution Width in Patients with Out-of-Hospital Cardiac Arrest: A Retrospective Study

Abstract

Abstract Background The ratio of hemoglobin to red blood cell distribution width (HRR) can reflect the degree of oxidative stress and systemic inflammatory response in the body, and is a potential indicator to predict the prognosis of patients with cardiac arrest (CA). Methods We retrospectively analyzed 126 patients successfully resuscitated after out-of-hospital cardiac arrest. Patients were grouped according to their survival status at discharge: 35 survived and 91 died. Binary logistic regression was used to analyze the independent factors affecting the prognosis of patients after cardiopulmonary resuscitation (CPR). A receiver operating characteristic (ROC) curve was used to analyze the predictive value of each independent factor for the prognosis of patients after CPR. Results The HRR in death group was lower than that in the survival group (P < 0.05), which was closely related to the prognosis of patients after CPR. The ROC curve showed that HRR < 8.555 (AUC = 0.733, sensitivity 87.5%, specificity 40.7%, P < 0.001) indicated poor prognosis after CPR. Conclusions The HRR is an independent risk factor for the prognosis in patients who underwent CPR after out-of-hospital cardiac arrest. After successful resuscitation, HRR lower than 8.555 indicates poor prognosis.

Keywords

• Cardiac arrest
• After cardiopulmonary resuscitation
• Hemoglobin
• Red blood cell distribution width
• Ratio
• Prognosis