Compartmentalized microbes and co-cultures in hydrogels for on-demand bioproduction and preservation

Trevor G. Johnston; Shuo-Fu Yuan; James M. Wagner; Xiunan Yi; Abhijit Saha; Patrick Smith; Alshakim Nelson; Hal S. Alper

doi:10.1038/s41467-020-14371-4

Nature Communications (Feb 2020)

Compartmentalized microbes and co-cultures in hydrogels for on-demand bioproduction and preservation

Trevor G. Johnston,
Shuo-Fu Yuan,
James M. Wagner,
Xiunan Yi,
Abhijit Saha,
Patrick Smith,
Alshakim Nelson,
Hal S. Alper

Affiliations

Trevor G. Johnston: Department of Chemistry, University of Washington
Shuo-Fu Yuan: Institute for Cellular and Molecular Biology, The University of Texas at Austin
James M. Wagner: McKetta Department of Chemical Engineering, The University of Texas at Austin
Xiunan Yi: Institute for Cellular and Molecular Biology, The University of Texas at Austin
Abhijit Saha: Department of Chemistry, University of Washington
Patrick Smith: Department of Chemistry, University of Washington
Alshakim Nelson: Department of Chemistry, University of Washington
Hal S. Alper: Institute for Cellular and Molecular Biology, The University of Texas at Austin

DOI: https://doi.org/10.1038/s41467-020-14371-4
Journal volume & issue: Vol. 11, no. 1
pp. 1 – 11

Abstract

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Large scale suspension fermentation technology is not easily portable or reusable. Here the authors describe a hydrogel system suitable for long-term and reusable production with both single and multi-organism consortia.

Published in Nature Communications

ISSN: 2041-1723 (Online)
Publisher: Nature Portfolio
Country of publisher: United Kingdom
LCC subjects: Science
Website: https://www.nature.com/ncomms/

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