Nature Communications (Apr 2020)

Sex chromosome evolution in parasitic nematodes of humans

  • Jeremy M. Foster,
  • Alexandra Grote,
  • John Mattick,
  • Alan Tracey,
  • Yu-Chih Tsai,
  • Matthew Chung,
  • James A. Cotton,
  • Tyson A. Clark,
  • Adam Geber,
  • Nancy Holroyd,
  • Jonas Korlach,
  • Yichao Li,
  • Silvia Libro,
  • Sara Lustigman,
  • Michelle L. Michalski,
  • Michael Paulini,
  • Matthew B. Rogers,
  • Laura Teigen,
  • Alan Twaddle,
  • Lonnie Welch,
  • Matthew Berriman,
  • Julie C. Dunning Hotopp,
  • Elodie Ghedin

DOI
https://doi.org/10.1038/s41467-020-15654-6
Journal volume & issue
Vol. 11, no. 1
pp. 1 – 12

Abstract

Read online

Many nematode worms, including Caenorhabditis elegans have XX/XO sex determination, while other species have XY. The authors use a new genome assembly of the filarial parasite Brugia malayi and published data to show that nematode sex chromosome evolution is highly plastic.