Etiopathogenetic therapy effect on the microcirculation of the bulbar conjunctiva in patients with dyslipidemia after COVID-19 associated pneumonia

Abstract

Purpose:to study the hemodynamics of the bulbar conjunctiva in patients with dyslipidemia and a history of COVID-19 associated pneumonia who received etiopathogenetic therapy. Material and methods. 54 patients (108 eyes) aged 61 ± 14 with a documented diagnosis of COVID-19-associated pneumonia and dyslipidemia were prospectively examined 3 months after the discharge from hospital. Patients were divided into two groups, identical in gender and age, depending on the presence or absence of metabolic syndrome. For 1 month, both groups received etiotropic therapy: statins, antioxidants thioctic acid pills and topical antioxidant instillations (1 % solution of Emoxipine®three times a day, and instillations of NSAID Broxinac®(in the form of 0.09 % Bromfenacum eyedrops) 1 drop 2 times a day. Results.Improvement was achieved in perivascular parameters (of 54 % of patients of group 1 and 50 % of patients of group 2); in the shape of bloodvessels (in 10 and 11 % of cases, respectively); intravascular parameters (in 71 and 78 %, respectively). Conclusion. The proposed etiopathogenetic therapy has a positive effect on the state of damaged bulbar conjunctiva microcirculation.

Keywords

• microcirculation
• covid-19
• dyslipidemia
• broxinac®
• thioctic acid
• emoxipine ®