mSystems (Aug 2021)

Metagenome-Wide Analysis of Rural and Urban Surface Waters and Sediments in Bangladesh Identifies Human Waste as a Driver of Antibiotic Resistance

  • Ross Stuart McInnes,
  • Md Hassan uz-Zaman,
  • Imam Taskin Alam,
  • Siu Fung Stanley Ho,
  • Robert A. Moran,
  • John D. Clemens,
  • Md Sirajul Islam,
  • Willem van Schaik

DOI
https://doi.org/10.1128/mSystems.00137-21
Journal volume & issue
Vol. 6, no. 4

Abstract

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Low- and middle-income countries (LMICs) have higher burdens of multidrug-resistant infections than high-income countries, and there is thus an urgent need to elucidate the drivers of the spread of antibiotic-resistant bacteria in LMICs. Here, we study the diversity and abundance of antibiotic resistance genes in surface water and sediments from rural and urban settings in Bangladesh.