4-Azatricyclo[5.2.2.02,6]undecane-3,5,8-triones as Potential Pharmacological Agents

Abstract

A series of twenty six arylpiperazine and aminoalkanol derivatives of 4-azatricyclo[ 5.2.2.02,6]undecane-3,5,8-trione have been prepared. The synthesized compounds were evaluated for their cytotoxicity and anti-HIV-1 activity in MT-4 cells.

Keywords

• 4-Azatricyclo[5.2.2.02
• 6]undecane-3
• 5
• 8-trione
• arylpiperazine derivatives
• crystal structure
• anti-HIV-1 activity