#21. PD-1 blockade induces bone loss and reduces bone strength in a breast cancer bone metastasis model

• Gwenyth J. Joseph,
• Lawrence A. Vecchi, III,
• Sasidhar Uppuganti,
• Margaret Durdan,
• Wei Chen,
• David Harrison,
• Jeffry S. Nyman,
• Megan Weivoda,
• Rachelle W. Johnson

Affiliations

Gwenyth J. Joseph

Program in Cancer Biology, Vanderbilt University, Nashville, TN, USA; Department of Medicine, Vanderbilt University Medical Center, Nashville, TN, USA

Lawrence A. Vecchi, III

Department of Medicine, Vanderbilt University Medical Center, Nashville, TN, USA

Sasidhar Uppuganti

Department of Orthopaedic Surgery, Vanderbilt University Medical Center, Nashville, TN, USA

Margaret Durdan

University of Michigan, Ann Arbor, USA; Mayo Clinic, Rochester, MN, USA

Wei Chen

Department of Medicine, Vanderbilt University Medical Center, Nashville, TN, USA

David Harrison

Department of Medicine, Vanderbilt University Medical Center, Nashville, TN, USA

Jeffry S. Nyman

Department of Orthopaedic Surgery, Vanderbilt University Medical Center, Nashville, TN, USA

Megan Weivoda

Mayo Clinic, Rochester, MN, USA

Rachelle W. Johnson

Program in Cancer Biology, Vanderbilt University, Nashville, TN, USA; Department of Medicine, Vanderbilt University Medical Center, Nashville, TN, USA