Structure of the herpes simplex virus type 2 C-capsid with capsid-vertex-specific component

Jialing Wang; Shuai Yuan; Dongjie Zhu; Hao Tang; Nan Wang; Wenyuan Chen; Qiang Gao; Yuhua Li; Junzhi Wang; Hongrong Liu; Xinzheng Zhang; Zihe Rao; Xiangxi Wang

doi:10.1038/s41467-018-06078-4

Nature Communications (Sep 2018)

Structure of the herpes simplex virus type 2 C-capsid with capsid-vertex-specific component

Jialing Wang,
Shuai Yuan,
Dongjie Zhu,
Hao Tang,
Nan Wang,
Wenyuan Chen,
Qiang Gao,
Yuhua Li,
Junzhi Wang,
Hongrong Liu,
Xinzheng Zhang,
Zihe Rao,
Xiangxi Wang

Affiliations

Jialing Wang: National Laboratory of Macromolecules, Institute of Biophysics, Chinese Academy of Science
Shuai Yuan: National Laboratory of Macromolecules, Institute of Biophysics, Chinese Academy of Science
Dongjie Zhu: National Laboratory of Macromolecules, Institute of Biophysics, Chinese Academy of Science
Hao Tang: College of Physics and Information Science, Synergetic Innovation Center for Quantum Effects and Applications, Key Laboratory of Low-dimensional Quantum Structures, and Quantum Control of the Ministry of Education, Hunan Normal University
Nan Wang: National Laboratory of Macromolecules, Institute of Biophysics, Chinese Academy of Science
Wenyuan Chen: College of Physics and Information Science, Synergetic Innovation Center for Quantum Effects and Applications, Key Laboratory of Low-dimensional Quantum Structures, and Quantum Control of the Ministry of Education, Hunan Normal University
Qiang Gao: National Laboratory of Macromolecules, Institute of Biophysics, Chinese Academy of Science
Yuhua Li: National Institutes for Food and Drug Control
Junzhi Wang: National Institutes for Food and Drug Control
Hongrong Liu: College of Physics and Information Science, Synergetic Innovation Center for Quantum Effects and Applications, Key Laboratory of Low-dimensional Quantum Structures, and Quantum Control of the Ministry of Education, Hunan Normal University
Xinzheng Zhang: National Laboratory of Macromolecules, Institute of Biophysics, Chinese Academy of Science
Zihe Rao: National Laboratory of Macromolecules, Institute of Biophysics, Chinese Academy of Science
Xiangxi Wang: National Laboratory of Macromolecules, Institute of Biophysics, Chinese Academy of Science

DOI: https://doi.org/10.1038/s41467-018-06078-4
Journal volume & issue: Vol. 9, no. 1
pp. 1 – 10

Abstract

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Herpes simplex virus type-2 (HSV-2) belongs to the α-herpesvirinae subfamily and is a sexually transmitted virus that causes genital ulcer disease. Here the authors present the 3.75 Å cryo-EM structure of the HSV-2 C-capsid with capsid-vertex-specific component and describe α-herpesvirus-specific structural features.

Published in Nature Communications

ISSN: 2041-1723 (Online)
Publisher: Nature Portfolio
Country of publisher: United Kingdom
LCC subjects: Science
Website: https://www.nature.com/ncomms/

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