620 Multimodal real world data reveals immunogenomic drivers of acquired and primary resistance to immune checkpoint blockade

• Ross Stewart,
• Mark Cobbold,
• Scott Hammond,
• Sajan Khosla,
• Roy Rabbie,
• Douglas C Palmer,
• Mohamed Reda Keddar,
• Sebastian Carrasco Pro,
• Kathleen Burke,
• Ana Stewart,
• Benjamin Sidders,
• Jonathan R Dry,
• Martin L Miller

Affiliations

Ross Stewart

Aff1 grid.417815.e0000000104335842MedImmune Cambridge UK

Mark Cobbold

Aff293 grid.32224.350000000403869924Massachusetts General Hospital Cancer Center Boston MA USA

Scott Hammond

Aff2 grid.418152.bMedImmune Gaithersburg MD USA

Sajan Khosla

2Quality and Outcomes Research Unit, University Hospital Birmingham NHS Foundation Trust, Queen Elizabeth Hospital, Birmingham, UK

Roy Rabbie

3Department of Acute Medicine, St George`s Hospital, London, UK

Douglas C Palmer

2AstraZeneca, Waltham, MA, USA

Mohamed Reda Keddar

1AstraZeneca, Cambridge, Cambridgeshire, UK

Sebastian Carrasco Pro

2Tempus Labs Inc, Boston, MA, USA

Kathleen Burke

2Tempus Labs Inc, Boston, MA, USA

Ana Stewart

1AstraZeneca, Cambridge, Cambridgeshire, UK

Benjamin Sidders

1AstraZeneca, Cambridge, Cambridgeshire, UK

Jonathan R Dry

2Tempus Labs Inc, Boston, MA, USA

Martin L Miller

1AstraZeneca, Cambridge, Cambridgeshire, UK