A cross-dehydrogenative C(sp 3)−H heteroarylation via photo-induced catalytic chlorine radical generation

Abstract

Hydrogen atom abstraction from C(sp 3)–H bonds of naturally abundant alkanes for alkyl radical generation represents a promising yet underexplored strategy in the alkylation reaction designs. Here the authors show a photo-induced and chemical oxidant-free cross-dehydrogenative coupling between alkanes and heteroarenes using catalytic chloride and cobalt catalyst.