VSTM1 regulates monocyte/macrophage function via the NF-κB signaling pathway

Abstract

V-set and transmembrane domain-containing protein 1 (VSTM1) is negatively correlated with inflammation. However, its effect on atherosclerosis (AS) remains largely unexplored. In this study, we aimed to assess the effect of VSTM1 on the biological function of human peripheral blood mononuclear cells /macrophages stimulated by oxidized low-density lipoprotein (ox-LDL).

Keywords

• vstm1
• monocyte/macrophage
• inflammation
• atherosclerosis
• nf-κb