2-(3,4-Dimethoxyphenyl)-<i>N</i>-(4-methoxyphenyl)-1-propyl-1<i>H</i>-benzo[<i>d</i>]imidazole-5-carboxamide

Abstract

2-(3,4-Dimethoxyphenyl)-N-(4-methoxyphenyl)-1-propyl-1H-benzo[d]imidazole-5-carboxamide was synthesized by the ‘one-pot’ reductive cyclization of N-(4-methoxyphenyl)-3-nitro-4-(propylamino)benzamide with 3,4-dimethoxybenzaldehyde, using sodium dithionite as a reductive cyclizing agent using DMSO as a solvent. The structure of newly synthesized compound was elucidated based on IR, 1H-NMR, 13C-NMR, and LC-MS data.

Keywords

• benzimidazole
• carboxamide
• one-pot synthesis
• reductive cyclization