Journal of Tropical Pharmacy and Chemistry (Jun 2021)

Activity of Tokulo (Kleinhovia hospita L.) as Anti Rheumatoid Arthritis and Anti-inflammatory in White Rats Induced by Complete Freud Adjuvant (CFA)

  • Fatma Sari Siharis,
  • Selpirahmawati Saranani,
  • Nurlansi Nurlansi

DOI
https://doi.org/10.25026/jtpc.v5i3.299
Journal volume & issue
Vol. 5, no. 3

Abstract

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Tokulo (Kleinhovia hospita) leaves are commonly used by Moronene people (Southeast Sulawesi) to treat headaches. This is supported scientifically from research which states that tokulo leaves have analgesic and anti-inflammatory activity. The NSAID group is included in the anti-rheumatoid arthritis therapy. To determine the anti-RA activity of this plant, a study was carried out on CFA-induced rats. Based on the results of the study, it is known that the ethanol extract of tokulo leaves has anti-RA and anti-inflammatory activity in CFA-induced rats. Keywords: Kleinhovia hospita, Rheumatoid Arthritis, Inflammation