Prostate cancer radiotherapy and incidental testicular irradiation: Impact on gonadal function

Abstract

Incidental testicular irradiation during prostate cancer radiotherapy is rarely documented in literature and the long-term impact on gonadal function largely underreported. Here we present an overview of available data on incidental testicular irradiation and radiation-induced hypogonadism during prostate cancer radiotherapy and discuss future technical developments to minimize testis irradiation.

Keywords

• Prostate cancer
• Radiotherapy
• Testicles
• Testosterone levels
• Sexual toxicity
• Hypogonadism