Recent advancements in organotin(IV) complexes of drugs: Synthesis, characterization, and application

Abstract

This review focuses on the synthesis, structural characterization, and biological activity of organotin complexes with drug such as non-steroidal anti-inflammatory drugs (NSAIDs)/quinolones. Organotin complexes have been widely studied due to their potential pharmacological applications, and the combination with drug provides an interesting approach for the development of new therapeutic agents. The review covers recent advances in the synthesis and characterization of organotin-NSAID/Quinolonescomplexes, including their spectroscopic and crystallographic properties with the help of X-ray crystallography. Moreover, the biological activity of these complexes is discussed, with a particular focus on their potential anti-inflammatory, anticancer, and antimicrobial properties. Results pertaining to the biological activities of these organotin complexes have been mentioned. The review highlights the importance of organotin complexes with NSAID/Quinolones in medicinal chemistry and the need for further studies to explore their potential as therapeutic agents.

Keywords

• Organotin
• NSAID
• QUINOLONES
• X-Ray crystallography
• Synthesis
• Anticancer