Nature Communications (Aug 2022)

Discrete subicular circuits control generalization of hippocampal seizures

  • Fan Fei,
  • Xia Wang,
  • Cenglin Xu,
  • Jiaying Shi,
  • Yiwei Gong,
  • Heming Cheng,
  • Nanxi Lai,
  • Yeping Ruan,
  • Yao Ding,
  • Shuang Wang,
  • Zhong Chen,
  • Yi Wang

DOI
https://doi.org/10.1038/s41467-022-32742-x
Journal volume & issue
Vol. 13, no. 1
pp. 1 – 17

Abstract

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The subiculum is known to contribute to seizures in epilepsy. Here the authors investigate the circuit mechanism by which the subiculum contributes to initiation and propagation of hippocampal seizures in a mouse model.