Efficacy of antivirals and mRNA vaccination against an XBF clinical isolate

• Ryuta Uraki,
• Mutsumi Ito,
• Maki Kiso,
• Seiya Yamayoshi,
• Kiyoko Iwatsuki-Horimoto,
• Yuko Sakai-Tagawa,
• Masaki Imai,
• Michiko Koga,
• Shinya Yamamoto,
• Eisuke Adachi,
• Makoto Saito,
• Takeya Tsutsumi,
• Amato Otani,
• Yukie Kashima,
• Tetsuhiro Kikuchi,
• James Theiler,
• Hiroshi Yotsuyanagi,
• Yutaka Suzuki,
• Bette Korber,
• Yoshihiro Kawaoka

Affiliations

Ryuta Uraki

Division of Virology, Institute of Medical Science, University of Tokyo, Tokyo, Japan; The Research Center for Global Viral Diseases, National Center for Global Health and Medicine Research Institute, Tokyo, Japan

Mutsumi Ito

Division of Virology, Institute of Medical Science, University of Tokyo, Tokyo, Japan

Maki Kiso

Division of Virology, Institute of Medical Science, University of Tokyo, Tokyo, Japan

Seiya Yamayoshi

Division of Virology, Institute of Medical Science, University of Tokyo, Tokyo, Japan; The Research Center for Global Viral Diseases, National Center for Global Health and Medicine Research Institute, Tokyo, Japan

Kiyoko Iwatsuki-Horimoto

Division of Virology, Institute of Medical Science, University of Tokyo, Tokyo, Japan

Yuko Sakai-Tagawa

Division of Virology, Institute of Medical Science, University of Tokyo, Tokyo, Japan

Masaki Imai

Division of Virology, Institute of Medical Science, University of Tokyo, Tokyo, Japan; The Research Center for Global Viral Diseases, National Center for Global Health and Medicine Research Institute, Tokyo, Japan

Michiko Koga

Department of Infectious Diseases and Applied Immunology, IMSUT Hospital of the Institute of Medical Science, University of Tokyo, Tokyo, Japan; Division of Infectious Diseases, Advanced Clinical Research Center, Institute of Medical Science, University of Tokyo, Tokyo, Japan

Shinya Yamamoto

Division of Virology, Institute of Medical Science, University of Tokyo, Tokyo, Japan; Division of Infectious Diseases, Advanced Clinical Research Center, Institute of Medical Science, University of Tokyo, Tokyo, Japan

Eisuke Adachi

Department of Infectious Diseases and Applied Immunology, IMSUT Hospital of the Institute of Medical Science, University of Tokyo, Tokyo, Japan

Makoto Saito

Department of Infectious Diseases and Applied Immunology, IMSUT Hospital of the Institute of Medical Science, University of Tokyo, Tokyo, Japan; Division of Infectious Diseases, Advanced Clinical Research Center, Institute of Medical Science, University of Tokyo, Tokyo, Japan

Takeya Tsutsumi

Department of Infectious Diseases and Applied Immunology, IMSUT Hospital of the Institute of Medical Science, University of Tokyo, Tokyo, Japan; Division of Infectious Diseases, Advanced Clinical Research Center, Institute of Medical Science, University of Tokyo, Tokyo, Japan

Amato Otani

Department of Infectious Diseases and Applied Immunology, IMSUT Hospital of the Institute of Medical Science, University of Tokyo, Tokyo, Japan

Yukie Kashima

Department of Computational Biology and Medical Sciences, Graduate School of Frontier Sciences, The University of Tokyo, Kashiwa, Chiba, Japan

Tetsuhiro Kikuchi

Clinic of Nihon Sumo Kyokai, Tokyo, Japan

James Theiler

Theoretical Biology and Biophysics, Los Alamos National Laboratory, Los Alamos, NM, 87545, USA; New Mexico Consortium, Los Alamos, NM, 87545, USA

Hiroshi Yotsuyanagi

Department of Infectious Diseases and Applied Immunology, IMSUT Hospital of the Institute of Medical Science, University of Tokyo, Tokyo, Japan; Division of Infectious Diseases, Advanced Clinical Research Center, Institute of Medical Science, University of Tokyo, Tokyo, Japan

Yutaka Suzuki

Department of Computational Biology and Medical Sciences, Graduate School of Frontier Sciences, The University of Tokyo, Kashiwa, Chiba, Japan

Bette Korber

Theoretical Biology and Biophysics, Los Alamos National Laboratory, Los Alamos, NM, 87545, USA; New Mexico Consortium, Los Alamos, NM, 87545, USA

Yoshihiro Kawaoka

Division of Virology, Institute of Medical Science, University of Tokyo, Tokyo, Japan; The Research Center for Global Viral Diseases, National Center for Global Health and Medicine Research Institute, Tokyo, Japan; Influenza Research Institute, Department of Pathobiological Sciences, School of Veterinary Medicine, University of Wisconsin–Madison, Madison, WI, USA; The University of Tokyo, Pandemic Preparedness, Infection and Advanced Research Center (UTOPIA), Tokyo, Japan; Corresponding author. Division of Virology, Institute of Medical Science, University of Tokyo, Tokyo, Japan.