Characteristics of production cytokines in patients with development of chronic tick-borne borreliosis

Abstract

For detection of cytokine production features in patients with development of chronic tick-borne borreliosis the evaluation of spontaneous, fitohaemagglutinin-stimulated and stimulated with antigen of borrelia cytokine production was conducted in supernatants of three-day blood cells cultures. High risk of development of chronic tick-borne borreliosis associated with intensive spontaneous and antigen-stimulated production of interferon-g and transforming growing factor-β1 in acute disease.

Keywords

• иксодовый клещевой боррелиоз
• интерлейкин-4
• интерферон-
• трансформирующий ростовой фактор β1