Primary Xanthoma of Ulnar Bone in a Normolipemic Patient

Abstract

Xanthoma of bone is an exceedingly rare primary bone lesion. It is generally known that bone xanthomas are associated with hyperlipidemia. Non-hyperlipidemic xanthomas are very rare. Radiologically it presents as well-defined osteolytic lesion thus mimicking benign bone tumours. Definitive diagnosis is based mainly on histopathology. Histologically, presence of sheets of foamy macrophages with multinucleated giant cells and cholesterol clefts at places confirms the diagnosis of xanthoma. Surgical curettage followed by bone grafting is curative. We report a case of skeletal xanthoma in ulnar bone of a non-hyperlipidemic patient.

Keywords

• Foamy macrophages
• Non-hyperlipidemia
• Osteolytic