Clinical and Molecular Allergy (May 2020)
Urticaria: recommendations from the Italian Society of Allergology, Asthma and Clinical Immunology and the Italian Society of Allergological, Occupational and Environmental Dermatology
- Eustachio Nettis,
- Caterina Foti,
- Marina Ambrifi,
- Ilaria Baiardini,
- Leonardo Bianchi,
- Alessandro Borghi,
- Marco Caminati,
- Giorgio Walter Canonica,
- Marco Casciaro,
- Laura Colli,
- Giselda Colombo,
- Monica Corazza,
- Antonio Cristaudo,
- Giulia De Feo,
- Ornella De Pita’,
- Mario Di Gioacchino,
- Elisabetta Di Leo,
- Filippo Fassio,
- Sebastiano Gangemi,
- Alessia Gatta,
- Katharina Hansel,
- Enrico Heffler,
- Cristoforo Incorvaia,
- Maddalena Napolitano,
- Cataldo Patruno,
- Silvia Peveri,
- Paolo Daniele Pigatto,
- Cristina Quecchia,
- Anna Radice,
- Giuseppe Alvise Ramirez,
- Paolo Romita,
- Franco Rongioletti,
- Oliviero Rossi,
- Eleonora Savi,
- Gianenrico Senna,
- Massimo Triggiani,
- Myriam Zucca,
- Enrico Maggi,
- Luca Stingeni
Affiliations
- Eustachio Nettis
- Department of Emergency and Organ Transplantation, School and Chair of Allergology and Clinical Immunology, University of Bari - Aldo Moro
- Caterina Foti
- Department of Biomedical Science and Human Oncology, Dermatological Clinic, University of Bari
- Marina Ambrifi
- San Gallicano Dermatological Institute -IRCCS
- Ilaria Baiardini
- Department of Biomedical Sciences, Humanitas University
- Leonardo Bianchi
- Section of Dermatology, Department of Medicine, University of Perugia
- Alessandro Borghi
- Section of Dermatology, Department of Medical Sciences, University of Ferrara
- Marco Caminati
- Asthma Center and Allergy Unit, University of Verona and General Hospital
- Giorgio Walter Canonica
- Department of Biomedical Sciences, Humanitas University
- Marco Casciaro
- School and Division of Allergy and Clinical Immunology, Department of Clinical and Experimental Medicine, University of Messina
- Laura Colli
- Department of Biomedical, Surgical and Dental Sciences, Clinical Dermatology, IRCCS Galeazzi Orthopaedic Institute, University of Milan
- Giselda Colombo
- Unit of Immunology, Rheumatology Allergy and Rare Diseases, IRCCS Ospedale San Raffaele
- Monica Corazza
- Section of Dermatology, Department of Medical Sciences, University of Ferrara
- Antonio Cristaudo
- San Gallicano Dermatological Institute -IRCCS
- Giulia De Feo
- Division of Allergy and Clinical Immunology, University of Salerno
- Ornella De Pita’
- Clinical Pathology and Immune Inflammatory Disease of the Skin, Cristo Re Hospital
- Mario Di Gioacchino
- Department of Medicine and Science on Ageing, School of Medicine, G. d’Annunzio University
- Elisabetta Di Leo
- Section of Allergy and Clinical Immunology, Unit of Internal Medicine, “F. Miulli” Hospital
- Filippo Fassio
- Allergy and Clinical Immunology Unit, Azienda USL Toscana Centro
- Sebastiano Gangemi
- School and Division of Allergy and Clinical Immunology, Department of Clinical and Experimental Medicine, University of Messina
- Alessia Gatta
- Department of Medicine and Science on Ageing, School of Medicine, G. d’Annunzio University
- Katharina Hansel
- Section of Dermatology, Department of Medicine, University of Perugia
- Enrico Heffler
- Department of Biomedical Sciences, Humanitas University
- Cristoforo Incorvaia
- Cardiac/Pulmonary Rehabilitation, ASST Pini-CTO
- Maddalena Napolitano
- Section of Dermatology, Department of Medicine and Health Sciences Vincenzo Tiberio, University of Molise
- Cataldo Patruno
- Department of Health Sciences, University Magna Graecia of Catanzaro
- Silvia Peveri
- Allergy Department Unit, Piacenza Hospital
- Paolo Daniele Pigatto
- Department of Biomedical, Surgical and Dental Sciences, Clinical Dermatology, IRCCS Galeazzi Orthopaedic Institute, University of Milan
- Cristina Quecchia
- Centro “Io e l’Asma”, Ospedale dei Bambini, ASST Spedali Civili
- Anna Radice
- Immunoallergology Unit, Careggi University Hospital
- Giuseppe Alvise Ramirez
- Unit of Immunology, Rheumatology Allergy and Rare Diseases, IRCCS Ospedale San Raffaele
- Paolo Romita
- Department of Biomedical Science and Human Oncology, Dermatological Clinic, University of Bari
- Franco Rongioletti
- Dermatological Clinic/UC of Dermatology, Department of Medical Science and Public Health, AOU Cagliari
- Oliviero Rossi
- Immunoallergology Unit, Careggi University Hospital
- Eleonora Savi
- Allergy Department Unit, Piacenza Hospital
- Gianenrico Senna
- Asthma Center and Allergy Unit, University of Verona and General Hospital
- Massimo Triggiani
- Division of Allergy and Clinical Immunology, University of Salerno
- Myriam Zucca
- Dermatological Clinic/UC of Dermatology, Department of Medical Science and Public Health, AOU Cagliari
- Enrico Maggi
- Department of Experimental and Clinical Medicine and Center of Excellence for Research, Transfer and High Education DENOTHE of the University of Florence
- Luca Stingeni
- Section of Dermatology, Department of Medicine, University of Perugia
- DOI
- https://doi.org/10.1186/s12948-020-00123-8
- Journal volume & issue
-
Vol. 18,
no. 1
pp. 1 – 19
Abstract
Abstract Background Urticaria is a disorder affecting skin and mucosal tissues characterized by the occurrence of wheals, angioedema or both, the latter defining the urticaria-angioedema syndrome. It is estimated that 12–22% of the general population has suffered at least one subtype of urticaria during life, but only a small percentage (estimated at 7.6–16%) has acute urticaria, because it is usually self-limited and resolves spontaneously without requiring medical attention. This makes likely that its incidence is underestimated. The epidemiological data currently available on chronic urticaria in many cases are deeply discordant and not univocal, but a recent Italian study, based on the consultation of a national registry, reports a prevalence of chronic spontaneous urticaria of 0.02% to 0.4% and an incidence of 0.1–1.5 cases/1000 inhabitants/year. Methods We reviewed the recent international guidelines about urticaria and we described a methodologic approach based on classification, pathophysiology, impact on quality of life, diagnosis and prognosis, differential diagnosis and management of all the types of urticaria. Conclusions The aim of the present document from the Italian Society of Allergology, Asthma and Clinical Immunology (SIAAIC) and the Italian Society of Allergological, Occupational and Environmental Dermatology (SIDAPA) is to provide updated information to all physicians involved in diagnosis and management of urticaria and angioedema.
Keywords