Synthesis and In Silico Evaluation of Piperazine-Substituted 2,3-Dichloro-5,8-dihydroxy-1,4-naphthoquinone Derivatives as Potential PARP‑1 Inhibitors

• Ulviyye Nemetova,
• Pınar Si̇yah,
• Tuğçe Boran,
• Çiğdem Bi̇lgi̇,
• Mustafa Özyürek,
• Sibel Şahi̇nler Ayla

Affiliations

Ulviyye Nemetova

Engineering Faculty, Department of Chemistry, Organic Chemistry, Istanbul University-Cerrahpaşa, Istanbul, Turkey

Pınar Si̇yah

Department of Biochemistry, Faculty of Pharmacy, Bahcesehir University, Istanbul, Turkey

Tuğçe Boran

Faculty of Pharmacy, Department of Pharmaceutical Toxicology, Istanbul University-Cerrahpaşa, Istanbul, Turkey

Çiğdem Bi̇lgi̇

Faculty of Pharmacy, Department of Pharmacognosy, Istanbul University-Cerrahpaşa, Istanbul, Turkey

Mustafa Özyürek

Engineering Faculty, Department of Chemistry, Analytical Chemistry, Istanbul University-Cerrahpaşa, Istanbul, Turkey

Sibel Şahi̇nler Ayla

Engineering Faculty, Department of Chemistry, Organic Chemistry, Istanbul University-Cerrahpaşa, Istanbul, Turkey