A Transferable IncC-IncX3 Hybrid Plasmid Cocarrying
bla
NDM-4
,
tet
(X), and
tmexCD3-toprJ3
Confers Resistance to Carbapenem and Tigecycline

Aki Hirabayashi; Trung Duc Dao; Taichiro Takemura; Futoshi Hasebe; Le Thi Trang; Nguyen Ha Thanh; Hoang Huy Tran; Keigo Shibayama; Ikuro Kasuga; Masato Suzuki

doi:10.1128/mSphere.00592-21

mSphere (Aug 2021)

A Transferable IncC-IncX3 Hybrid Plasmid Cocarrying bla NDM-4 , tet (X), and tmexCD3-toprJ3 Confers Resistance to Carbapenem and Tigecycline

Aki Hirabayashi,
Trung Duc Dao,
Taichiro Takemura,
Futoshi Hasebe,
Le Thi Trang,
Nguyen Ha Thanh,
Hoang Huy Tran,
Keigo Shibayama,
Ikuro Kasuga,
Masato Suzuki

Affiliations

Aki Hirabayashi: Antimicrobial Resistance Research Center, National Institute of Infectious Diseases, Tokyo, Japan
Trung Duc Dao: Vietnam Research Station, Center for Infectious Disease Research in Asia and Africa, Institute of Tropical Medicine, Nagasaki University, Nagasaki, Japan
Taichiro Takemura: Vietnam Research Station, Center for Infectious Disease Research in Asia and Africa, Institute of Tropical Medicine, Nagasaki University, Nagasaki, Japan
Futoshi Hasebe: Vietnam Research Station, Center for Infectious Disease Research in Asia and Africa, Institute of Tropical Medicine, Nagasaki University, Nagasaki, Japan
Le Thi Trang: National Institute of Hygiene and Epidemiology, Hanoi, Vietnam
Nguyen Ha Thanh: National Institute of Hygiene and Epidemiology, Hanoi, Vietnam
Hoang Huy Tran: National Institute of Hygiene and Epidemiology, Hanoi, Vietnam
Keigo Shibayama: Nagoya University Graduate School of Medicine, Nagoya, Japan
Ikuro Kasuga: Vietnam-Japan University, Vietnam National University, Hanoi, Vietnam
Masato Suzuki: ORCiD; Antimicrobial Resistance Research Center, National Institute of Infectious Diseases, Tokyo, Japan

DOI: https://doi.org/10.1128/mSphere.00592-21
Journal volume & issue: Vol. 6, no. 4

Abstract

Read online

Tigecycline is important as a last-resort antimicrobial and effective against antimicrobial-resistant bacteria, such as carbapenem-producing EnterobacteralestettmexCD-toprJ

Published in mSphere

ISSN: 2379-5042 (Online)
Publisher: American Society for Microbiology
Country of publisher: United States
LCC subjects: Science: Microbiology
Website: https://journals.asm.org/journal/msphere

About the journal