Optogenetic manipulation of a value-coding pathway from the primate caudate tail facilitates saccadic gaze shift

Hidetoshi Amita; Hyoung F. Kim; Ken-ichi Inoue; Masahiko Takada; Okihide Hikosaka

doi:10.1038/s41467-020-15802-y

Nature Communications (Apr 2020)

Optogenetic manipulation of a value-coding pathway from the primate caudate tail facilitates saccadic gaze shift

Hidetoshi Amita,
Hyoung F. Kim,
Ken-ichi Inoue,
Masahiko Takada,
Okihide Hikosaka

Affiliations

Hidetoshi Amita: Laboratory of Sensorimotor Research, National Eye Institute, National Institutes of Health
Hyoung F. Kim: School of Biological Sciences, Seoul National University
Ken-ichi Inoue: Systems Neuroscience Section, Primate Research Institute, Kyoto University
Masahiko Takada: Systems Neuroscience Section, Primate Research Institute, Kyoto University
Okihide Hikosaka: Laboratory of Sensorimotor Research, National Eye Institute, National Institutes of Health

DOI: https://doi.org/10.1038/s41467-020-15802-y
Journal volume & issue: Vol. 11, no. 1
pp. 1 – 13

Abstract

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The caudate tail encodes the stable value associated with visual objects and modulates gaze accordingly. Here, the authors use pathway-specific optogenetic manipulation of the caudate terminals in the substantia nigra pars reticulata on oculomotor behaviour.

Published in Nature Communications

ISSN: 2041-1723 (Online)
Publisher: Nature Portfolio
Country of publisher: United Kingdom
LCC subjects: Science
Website: https://www.nature.com/ncomms/

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