Docetaxel- induced organising pneumonia in a patient with advanced breast cancer: case report

Abstract

Pulmonary toxicity is a rare complication of taxanes, which are used in chemotherapy regimes in advanced breast carcinoma. We report a case of a 47- year- old woman with locally advanced breast carcinoma who developed organizing pneumonia following docetaxel based neoadjuvant chemotherapy. Following exclusion of infective causes, she was treated with prednisolone, resulting in a remarkable clinical and radiological resolution on high resolution computed tomography. Early identification and judicious steroid therapy can provide excellent outcomes in patients with docetaxel induced interstitial lung disease despite reported high morbidity and mortality.

Keywords

• Organising pneumonia
• Docetaxel
• Advanced breast carcinoma