Relationship Between HbA1c Level and Triglyceride/HDL Cholesterol Ratio and Triglyceride Glucose Index in Diabetes Patients

Abstract

Objective:To compare HbA1c level with triglyceride/HDL cholesterol (TG/HDL-C) ratio and triglyceride glucose (TyG) Index and to show its relationship with HbA1c level.Method:Our study was carried out retrospectively on patients who applied to the Department of General Internal Medicine, Sivas Cumhuriyet University Hospital, Turkey, between January 1, 2015 and January 1, 2020. The study is a retrospective review of 2,938 patients. HbA1c, triglyceride, and glucose values of the patients were recorded. TyG index and TG/HDL-C) ratio were found by calculating. Patients were grouped according to their HbA1c levels, TyG index and triglyceride/HDL cholesterol ratios.Results:We found that the TG/HDL-C ratio and the TyG index were statistically significantly lower as the HbA1c level decreased. When we grouped the patients according to their gender, we found that male patients had higher HbA1c, higher TyG index and TG/HDL-C ratio than female patients.Conclusion:We found a positive correlation between HbA1c levels and TG/HDL-C ratio and TyG index. Considering other studies in the literature, according to the results of our study, we predict an increased risk of coronary artery disease and cerebrovascular disease in patients with poor glycemic control.

Keywords

• diabetes mellitus
• triglyceride glucose index
• triglyceride/hdl cholesterol ratio