Recent advances in understanding Pseudomonas aeruginosa as a pathogen [version 1; referees: 3 approved]

Abstract

The versatile and ubiquitous Pseudomonas aeruginosa is an opportunistic pathogen causing acute and chronic infections in predisposed human subjects. Here we review recent progress in understanding P. aeruginosa population biology and virulence, its cyclic di-GMP-mediated switches of lifestyle, and its interaction with the mammalian host as well as the role of the type III and type VI secretion systems in P. aeruginosa infection.

Keywords

• Bacterial Infections
• Cellular Microbiology & Pathogenesis
• Immunity to Infections
• Innate Immunity
• Leukocyte Signaling & Gene Expression
• Medical Microbiology
• Microbial Evolution & Genomics
• Microbial Physiology & Metabolism
• Respiratory Infections
• Respiratory Pediatrics