Nature Communications (Aug 2017)
The non-coding RNA landscape of human hematopoiesis and leukemia
- Adrian Schwarzer,
- Stephan Emmrich,
- Franziska Schmidt,
- Dominik Beck,
- Michelle Ng,
- Christina Reimer,
- Felix Ferdinand Adams,
- Sarah Grasedieck,
- Damian Witte,
- Sebastian Käbler,
- Jason W. H. Wong,
- Anushi Shah,
- Yizhou Huang,
- Razan Jammal,
- Aliaksandra Maroz,
- Mojca Jongen-Lavrencic,
- Axel Schambach,
- Florian Kuchenbauer,
- John E. Pimanda,
- Dirk Reinhardt,
- Dirk Heckl,
- Jan-Henning Klusmann
Affiliations
- Adrian Schwarzer
- Institute of Experimental Hematology, Hannover Medical School
- Stephan Emmrich
- Pediatric Hematology and Oncology, Hannover Medical School
- Franziska Schmidt
- Pediatric Hematology and Oncology, Hannover Medical School
- Dominik Beck
- Lowy Cancer Research Centre and the Prince of Wales Clinical School, UNSW Australia
- Michelle Ng
- Pediatric Hematology and Oncology, Hannover Medical School
- Christina Reimer
- Pediatric Hematology and Oncology, Hannover Medical School
- Felix Ferdinand Adams
- Institute of Experimental Hematology, Hannover Medical School
- Sarah Grasedieck
- Department of Internal Medicine III, University Hospital of Ulm
- Damian Witte
- Pediatric Hematology and Oncology, Hannover Medical School
- Sebastian Käbler
- Pediatric Hematology and Oncology, Hannover Medical School
- Jason W. H. Wong
- Lowy Cancer Research Centre and the Prince of Wales Clinical School, UNSW Australia
- Anushi Shah
- Lowy Cancer Research Centre and the Prince of Wales Clinical School, UNSW Australia
- Yizhou Huang
- Lowy Cancer Research Centre and the Prince of Wales Clinical School, UNSW Australia
- Razan Jammal
- Pediatric Hematology and Oncology, Hannover Medical School
- Aliaksandra Maroz
- Pediatric Hematology and Oncology, Hannover Medical School
- Mojca Jongen-Lavrencic
- Department of Hematology, Erasmus University Medical Center
- Axel Schambach
- Institute of Experimental Hematology, Hannover Medical School
- Florian Kuchenbauer
- Department of Internal Medicine III, University Hospital of Ulm
- John E. Pimanda
- Lowy Cancer Research Centre and the Prince of Wales Clinical School, UNSW Australia
- Dirk Reinhardt
- Clinic for Pediatrics III, University Hospital Essen
- Dirk Heckl
- Pediatric Hematology and Oncology, Hannover Medical School
- Jan-Henning Klusmann
- Pediatric Hematology and Oncology, Hannover Medical School
- DOI
- https://doi.org/10.1038/s41467-017-00212-4
- Journal volume & issue
-
Vol. 8,
no. 1
pp. 1 – 17
Abstract
While micro-RNAs are known regulators of haematopoiesis and leukemogenesis, the role of long non-coding RNAs is less clear. Here the authors provide a non-coding RNA expression landscape of the human hematopoietic system, highlighting their role in the formation and maintenance of the human blood hierarchy.
