Near-infrared fluorescence imaging with indocyanine green in diabetic patient with critical limb ischemia: a case report

Abstract

A case report of type 2 diabetic patient with critical limb ischemia (CLI) after successful endovascular revascularization is reported. The diagnosis of CLI was established according to clinical data and results of lower limb ischemia assessment by non-invasive methods. The unique feature of this case is presentation of results of the new method of lower limb ischemia assessment – fluorescent angiography in near infrared range using indocyanine green (ICG). Following parameters of fluorescent angiography in near infrared range are analyzed in different regions of interest: Tstart(sec) – the time of fluorescence occurrence (Istart, unit) in the analyzed area after intravenous administration of ICG; Tmax (sec) – time to achieve maximum fluorescence (Imax, unit) after intravenous injection of ICG; Tmax – Tstart (sec) – the time difference between Imax and Istart. In this clinical case, the time of achievement Istart, Imax, Tmax – Tstart in different regions of interest decreased after successful endovascular revascularization of lower limb arteries.

Keywords

• diabetes mellitus
• peripheral artery disease
• critical limb ischemia
• endovascular treatment
• near infrared fluorescence angiography
• indocyanine green fluorescence angiography
• diabetic foot
• foot ulcer