Cytotoxicity and antioxidant activity of new biologically active constituents from Micromeria nervosa grown in Egypt

Abstract

Chromatographic fractionation of the acetone extract of Micromeria nervosa, resulted in the isolation and identification of new natural furanosesquiterpene alcohol; micromeriol (1), a known sterol; β-sitosterol (2), a new natural 5-β-cholestane type; nervosane (3), two known triterpenic acids; oleanolic acid (4), and ursolic acid (5). The cytotoxicity and the antioxidant activities of the acetone extract and the isolated pure compounds (1–5) were determined.

Keywords

• Lamiaceae
• Micromeria
• Furanosesquiterpene
• 5-β-Cholestane
• Cytotoxicity