Nature Communications (Nov 2022)
Structural basis for recognition of transcriptional terminator structures by ProQ/FinO domain RNA chaperones
- Hyeong Jin Kim,
- Mazzen Black,
- Ross A. Edwards,
- Flora Peillard-Fiorente,
- Rashmi Panigrahi,
- David Klingler,
- Reiner Eidelpes,
- Ricarda Zeindl,
- Shiyun Peng,
- Jikun Su,
- Ayat R. Omar,
- Andrew M. MacMillan,
- Christoph Kreutz,
- Martin Tollinger,
- Xavier Charpentier,
- Laetitia Attaiech,
- J. N. Mark Glover
Affiliations
- Hyeong Jin Kim
- Department of Biochemistry, University of Alberta
- Mazzen Black
- Department of Biochemistry, University of Alberta
- Ross A. Edwards
- Department of Biochemistry, University of Alberta
- Flora Peillard-Fiorente
- CIRI, Centre International de Recherche en Infectiologie, Team “Horizontal gene transfer in bacterial pathogens”, Inserm, U1111, Université Claude Bernard Lyon 1, CNRS, UMR5308, Ecole Normale Supérieure de Lyon, Université de Lyon
- Rashmi Panigrahi
- Department of Biochemistry, University of Alberta
- David Klingler
- Institute of Organic Chemistry, Center for Molecular Biosciences Innsbruck (CMBI), University of Innsbruck
- Reiner Eidelpes
- Institute of Organic Chemistry, Center for Molecular Biosciences Innsbruck (CMBI), University of Innsbruck
- Ricarda Zeindl
- Institute of Organic Chemistry, Center for Molecular Biosciences Innsbruck (CMBI), University of Innsbruck
- Shiyun Peng
- Department of Biochemistry, University of Alberta
- Jikun Su
- Department of Biochemistry, University of Alberta
- Ayat R. Omar
- Department of Biochemistry, University of Alberta
- Andrew M. MacMillan
- Department of Biochemistry, University of Alberta
- Christoph Kreutz
- Institute of Organic Chemistry, Center for Molecular Biosciences Innsbruck (CMBI), University of Innsbruck
- Martin Tollinger
- Institute of Organic Chemistry, Center for Molecular Biosciences Innsbruck (CMBI), University of Innsbruck
- Xavier Charpentier
- CIRI, Centre International de Recherche en Infectiologie, Team “Horizontal gene transfer in bacterial pathogens”, Inserm, U1111, Université Claude Bernard Lyon 1, CNRS, UMR5308, Ecole Normale Supérieure de Lyon, Université de Lyon
- Laetitia Attaiech
- CIRI, Centre International de Recherche en Infectiologie, Team “Horizontal gene transfer in bacterial pathogens”, Inserm, U1111, Université Claude Bernard Lyon 1, CNRS, UMR5308, Ecole Normale Supérieure de Lyon, Université de Lyon
- J. N. Mark Glover
- Department of Biochemistry, University of Alberta
- DOI
- https://doi.org/10.1038/s41467-022-34875-5
- Journal volume & issue
-
Vol. 13,
no. 1
pp. 1 – 12
Abstract
In this work, the authors determine the crystal structure of a ProQ/FinO RNA chaperone bound to its RNA target. This provides insight into how this family of bacterial proteins recognize transcriptional terminator structures.
