Nature Communications (Nov 2020)
Cellular events of acute, resolving or progressive COVID-19 in SARS-CoV-2 infected non-human primates
- M. D. Fahlberg,
- R. V. Blair,
- L. A. Doyle-Meyers,
- C. C. Midkiff,
- G. Zenere,
- K. E. Russell-Lodrigue,
- C. J. Monjure,
- E. H. Haupt,
- T. P. Penney,
- G. Lehmicke,
- B. M. Threeton,
- N. Golden,
- P. K. Datta,
- C. J. Roy,
- R. P. Bohm,
- N. J. Maness,
- T. Fischer,
- J. Rappaport,
- M. Vaccari
Affiliations
- M. D. Fahlberg
- Tulane National Primate Research Center
- R. V. Blair
- Tulane National Primate Research Center
- L. A. Doyle-Meyers
- Tulane National Primate Research Center
- C. C. Midkiff
- Tulane National Primate Research Center
- G. Zenere
- Tulane National Primate Research Center
- K. E. Russell-Lodrigue
- Tulane National Primate Research Center
- C. J. Monjure
- Tulane National Primate Research Center
- E. H. Haupt
- Tulane National Primate Research Center
- T. P. Penney
- Tulane National Primate Research Center
- G. Lehmicke
- Tulane National Primate Research Center
- B. M. Threeton
- Tulane National Primate Research Center
- N. Golden
- Tulane National Primate Research Center
- P. K. Datta
- Tulane National Primate Research Center
- C. J. Roy
- Tulane National Primate Research Center
- R. P. Bohm
- Tulane National Primate Research Center
- N. J. Maness
- Tulane National Primate Research Center
- T. Fischer
- Tulane National Primate Research Center
- J. Rappaport
- Tulane National Primate Research Center
- M. Vaccari
- Tulane National Primate Research Center
- DOI
- https://doi.org/10.1038/s41467-020-19967-4
- Journal volume & issue
-
Vol. 11,
no. 1
pp. 1 – 14
Abstract
Here, Fahlberg et al. describe the cellular immune response during acute, resolving or progressive COVID-19 in SARS-CoV-2 infected non-human primates. The study identifies associations of monocytes and macrophage subtypes in lungs with disease outcome, IL-6 and IL-10 ratio in plasma, and viral replication in bronchial brushes.
