American Journal of Ophthalmology Case Reports (Mar 2021)

A rare case of bilateral conjunctival Kaposi's sarcoma in a HIV-negative patient

  • Federica Fossataro,
  • Adriana Iuliano,
  • Giovanni Uccello,
  • Vittoria Lanni,
  • Luca D'Andrea,
  • Massimo Mascolo,
  • Antonio Travaglino,
  • Fausto Tranfa

Journal volume & issue
Vol. 21
p. 101024

Abstract

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Purpose: Kaposi's sarcoma (KS) is a rare multi-centric vascular neoplasm, first described by Moritz Kaposi in 1872. It can appear in four different forms: classic, endemic, HIV-related and post-transplant form. We present an uncommon case of seronegative HIV infection patient with skin KS involving conjunctiva of both eyes. Observations: Firstly, right eye lesions were surgically removed. Subsequently, the patient was administered with systemic chemotherapy (doxorubicin) to treat both skin and left eye lesions. No signs of recurrence were observed at 20 months’ follow-up. Conclusions: Both eyes involvement in KS is rarely described in scientific literature. Both surgery and chemotherapy could be considered valid treatment options for conjunctival KS.

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