Cardiovascular Complications of Acetylcholinesterase Inhibitors in Patients with Alzheimer’s Disease: A Narrative Review

Abstract

While acetylcholinesterase inhibitors are used to treat a wide range of patients with Alzheimer’s disease, acetylcholinesterase inhibitor use has also been associated with a variety of cardiovascular complications, including bradycardia and syncope. Herein, we review the pathophysiology and clinical evidence for cardiovascular complications caused by acetylcholinesterase inhibitors in patients being treated for dementia and discuss options for their management.

Keywords

• cholinesterase inhibitors
• alzheimer disease
• cardiovascular agents
• drug monitoring