Heliyon (Jun 2024)

Phytochemical property and antimicrobial activity of Ficifolius A. Rich root extract: Advancing Ethiopian indigenous wart curing medicinal plant

  • Yassin Adem,
  • kedir Yesuf,
  • Solomon Getachew,
  • kedir Derbie

Journal volume & issue
Vol. 10, no. 11
p. e31921

Abstract

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Although there may be a number of disadvantages, many patients prefer the traditional medication over surgical wart therapy since it may permanently remove the abscess from the body. The roots of the Ficifolius A. Rich plant are one of the native plants used in Ethiopia for traditional wart treatment. Therefore, the main goal of the research was to examine the phytochemical characteristics, identify the chemical compounds, and assess the antimicrobial effectiveness of the previously described plant root extract against gram-positive Staphylococcus aureus and gram-negative Escherichia coli pathogenic bacteria. Consequently, phytochemical characteristics such as tannins, alkaloids, flavonoids, phenols, and saponin were perceived, which inferred the therapeutic implications of root extracts. Furthermore, gas chromatography-mass spectrometry investigations identified a number of chemical components, including the particular antiviral substance Squalene. Moreover, antibacterial test results showed that the growth of gram-positive and gram-negative bacteria was inhibited with the application of crude extract. Generally, Ficifolius A. rich root extract could be effectively utilized for the treatment of anal warts.

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