Журнал микробиологии, эпидемиологии и иммунобиологии (Dec 2016)

DETERMINATION OF VIRULENCE PROPERTIES OF PATHOGENIC MICROORGANISMS IN VITRO: STATE-OF-ART

  • T. P. Shmelkova,
  • E. V. Sazanova,
  • A. L. Kravtsov,
  • T. A. Malyukova,
  • Yu. A. Popov,
  • A. V. Boiko,
  • Z. L. Devdariani,
  • T. N. Schukovskaya

DOI
https://doi.org/10.36233/0372-9311-2016-6-100-108
Journal volume & issue
Vol. 0, no. 6
pp. 100 – 108

Abstract

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Various methods for evaluation of virulence properties of causative agents of infectious diseases in vitro were analyzed: molecular-genetic, cultural-biochemical, immunologic, physiologic. Predominant use of molecular-genetic methods, expediency of a complex approach, relevance of search of novel informative parameters of virulence are noted. Study of biological properties of pathogens in vitro is the first screening stage of evaluation of their virulence.

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