Spectrin-beta 2 facilitates the selective accumulation of GABAA receptors at somatodendritic synapses

Joshua L. Smalley; Noell Cho; Shu Fun Josephine Ng; Catherine Choi; Abigail H. S. Lemons; Saad Chaudry; Christopher E. Bope; Jake S. Dengler; Chuansheng Zhang; Matthew N. Rasband; Paul A. Davies; Stephen J. Moss

doi:10.1038/s42003-022-04381-x

Communications Biology (Jan 2023)

Spectrin-beta 2 facilitates the selective accumulation of GABAA receptors at somatodendritic synapses

Joshua L. Smalley,
Noell Cho,
Shu Fun Josephine Ng,
Catherine Choi,
Abigail H. S. Lemons,
Saad Chaudry,
Christopher E. Bope,
Jake S. Dengler,
Chuansheng Zhang,
Matthew N. Rasband,
Paul A. Davies,
Stephen J. Moss

Affiliations

Joshua L. Smalley: Department of Neuroscience, Tufts University
Noell Cho: Department of Neuroscience, Tufts University
Shu Fun Josephine Ng: Department of Neuroscience, Tufts University
Catherine Choi: Department of Neuroscience, Tufts University
Abigail H. S. Lemons: Department of Neuroscience, Tufts University
Saad Chaudry: Department of Neuroscience, Tufts University
Christopher E. Bope: Department of Neuroscience, Tufts University
Jake S. Dengler: Department of Neuroscience, Tufts University
Chuansheng Zhang: Department of Neuroscience, Baylor College of Medicine
Matthew N. Rasband: Department of Neuroscience, Baylor College of Medicine
Paul A. Davies: Department of Neuroscience, Tufts University
Stephen J. Moss: Department of Neuroscience, Tufts University

DOI: https://doi.org/10.1038/s42003-022-04381-x
Journal volume & issue: Vol. 6, no. 1
pp. 1 – 13

Abstract

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The subunit composition of GABAA receptors and their interaction with beta spectrin complexes influences their localization between the neuronal axon initial segment or dendrites.

Published in Communications Biology

ISSN: 2399-3642 (Online)
Publisher: Nature Portfolio
Country of publisher: United Kingdom
LCC subjects: Science: Biology (General)
Website: https://www.nature.com/commsbio/

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