Combined treatment of dyslipoproteinemia in patients with atherosclerosis

Abstract

OBJECTIVE. The article analyzed the results of application of combined dyslipoproteinemia treatment including partial ileoshunting operation in combination with statins. MATERIAL AND METHODS. The dynamics of blood lipid levels during combined treatment of dyslipoproteinemia was studied in 56 patients with different clinical manifestations of atherosclerosis. RESULTS. Combined hypolipidemic therapy reduced total cholesterol levels by 42,3 % and LDL-cholesterol by 54,7 %, increased HDL-cholesterol by 24 % and decreased atherogenic index of plasma by 61,8 %. CONCLUSIONS. The application of atorvastatin therapy using10 mg/day allowed doctors to decrease the preoperative concentration of LDL-cholesterol levels twice in majority of cases (81,3 %). This method was used for patients who underwent partial ileoshunting operation because of acquired dyslipoproteinemia.

Keywords

• atherosclerosis
• dyslipoproteinemia
• ischemic heart disease
• obliterating atherosclerosis of the lower extremity vessels
• partial ileoshunting
• statins