Nature Communications (Jan 2023)
Sex-specificity of the C. elegans metabolome
- Russell N. Burkhardt,
- Alexander B. Artyukhin,
- Erin Z. Aprison,
- Brian J. Curtis,
- Bennett W. Fox,
- Andreas H. Ludewig,
- Diana Fajardo Palomino,
- Jintao Luo,
- Amaresh Chaturbedi,
- Oishika Panda,
- Chester J. J. Wrobel,
- Victor Baumann,
- Douglas S. Portman,
- Siu Sylvia Lee,
- Ilya Ruvinsky,
- Frank C. Schroeder
Affiliations
- Russell N. Burkhardt
- Boyce Thompson Institute and Department of Chemistry and Chemical Biology, Cornell University
- Alexander B. Artyukhin
- Boyce Thompson Institute and Department of Chemistry and Chemical Biology, Cornell University
- Erin Z. Aprison
- Department of Molecular Biosciences, Northwestern University
- Brian J. Curtis
- Boyce Thompson Institute and Department of Chemistry and Chemical Biology, Cornell University
- Bennett W. Fox
- Boyce Thompson Institute and Department of Chemistry and Chemical Biology, Cornell University
- Andreas H. Ludewig
- Boyce Thompson Institute and Department of Chemistry and Chemical Biology, Cornell University
- Diana Fajardo Palomino
- Boyce Thompson Institute and Department of Chemistry and Chemical Biology, Cornell University
- Jintao Luo
- Department of Biomedical Genetics, University of Rochester
- Amaresh Chaturbedi
- Department of Molecular Biology and Genetics, Cornell University
- Oishika Panda
- Boyce Thompson Institute and Department of Chemistry and Chemical Biology, Cornell University
- Chester J. J. Wrobel
- Boyce Thompson Institute and Department of Chemistry and Chemical Biology, Cornell University
- Victor Baumann
- Boyce Thompson Institute and Department of Chemistry and Chemical Biology, Cornell University
- Douglas S. Portman
- Department of Biomedical Genetics, University of Rochester
- Siu Sylvia Lee
- Department of Molecular Biology and Genetics, Cornell University
- Ilya Ruvinsky
- Department of Molecular Biosciences, Northwestern University
- Frank C. Schroeder
- Boyce Thompson Institute and Department of Chemistry and Chemical Biology, Cornell University
- DOI
- https://doi.org/10.1038/s41467-023-36040-y
- Journal volume & issue
-
Vol. 14,
no. 1
pp. 1 – 15
Abstract
Biological sex affects all aspects of animal physiology. Using the model C. elegans, the authors show that metabolomes are highly sex-specific and include a vast space of yet unidentified metabolites that may control development and lifespan.
