Nanomaterials (Sep 2021)

Recent Advances of Upconversion Nanomaterials in the Biological Field

  • Cunjin Gao,
  • Pengrui Zheng,
  • Quanxiao Liu,
  • Shuang Han,
  • Dongli Li,
  • Shiyong Luo,
  • Hunter Temple,
  • Christina Xing,
  • Jigang Wang,
  • Yanling Wei,
  • Tao Jiang,
  • Wei Chen

DOI
https://doi.org/10.3390/nano11102474
Journal volume & issue
Vol. 11, no. 10
p. 2474

Abstract

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Rare Earth Upconversion nanoparticles (UCNPs) are a type of material that emits high-energy photons by absorbing two or more low-energy photons caused by the anti-stokes process. It can emit ultraviolet (UV) visible light or near-infrared (NIR) luminescence upon NIR light excitation. Due to its excellent physical and chemical properties, including exceptional optical stability, narrow emission band, enormous Anti-Stokes spectral shift, high light penetration in biological tissues, long luminescent lifetime, and a high signal-to-noise ratio, it shows a prodigious application potential for bio-imaging and photodynamic therapy. This paper will briefly introduce the physical mechanism of upconversion luminescence (UCL) and focus on their research progress and achievements in bio-imaging, bio-detection, and photodynamic therapy.

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