Relevance of Brain 18F-FDG PET Imaging in Probable Seronegative Encephalitis With Catatonia: A Case Report

Michaël Guetta; Aurélie Kas; Aveline Aouidad; Marine Soret; Yves Allenbach; Manon Bordonné; Alice Oppetit; Marie Raffin; Dimitri Psimaras; David Cohen; David Cohen; David Cohen; Angèle Consoli; Angèle Consoli

doi:10.3389/fpsyt.2021.685711

Frontiers in Psychiatry (Jun 2021)

Relevance of Brain 18F-FDG PET Imaging in Probable Seronegative Encephalitis With Catatonia: A Case Report

Michaël Guetta,
Aurélie Kas,
Aveline Aouidad,
Marine Soret,
Yves Allenbach,
Manon Bordonné,
Alice Oppetit,
Marie Raffin,
Dimitri Psimaras,
David Cohen,
David Cohen,
David Cohen,
Angèle Consoli,
Angèle Consoli

Affiliations

Michaël Guetta: Department of Child and Adolescent Psychiatry, APHP. SU, Pitié-Salpêtrière Hospital, Paris, France
Aurélie Kas: Department of Nuclear Medicine, APHP. SU, Pitié-Salpêtrière Hospital, LIB, INSERM U1146, Paris, France
Aveline Aouidad: Department of Child and Adolescent Psychiatry, APHP. SU, Pitié-Salpêtrière Hospital, Paris, France
Marine Soret: Department of Nuclear Medicine, APHP. SU, Pitié-Salpêtrière Hospital, LIB, INSERM U1146, Paris, France
Yves Allenbach: Sorbonne-University, Internal Medecine and Clinical Immunlogy Departement, Paris, France
Manon Bordonné: University of Lorraine, Department of Nuclear Medicine and Nancyclotep Imaging Platform, CHRU Nancy, Nancy, France
Alice Oppetit: Department of Child and Adolescent Psychiatry, APHP. SU, Pitié-Salpêtrière Hospital, Paris, France
Marie Raffin: Department of Child and Adolescent Psychiatry, APHP. SU, Pitié-Salpêtrière Hospital, Paris, France
Dimitri Psimaras: Department of Neurology, APHP. SU, Pitié-Salpêtrière Hospital, Paris, France
David Cohen: Department of Child and Adolescent Psychiatry, APHP. SU, Pitié-Salpêtrière Hospital, Paris, France
David Cohen: CNRS UMR 7222, Institute for Intelligent Systems and Robotics, Sorbonne University, Paris, France
David Cohen: National Center for Rare Psychiatric Diseases, APHP. SU, Pitié-Salpêtrière Hospital, Paris, France
Angèle Consoli: Department of Child and Adolescent Psychiatry, APHP. SU, Pitié-Salpêtrière Hospital, Paris, France
Angèle Consoli: National Center for Rare Psychiatric Diseases, APHP. SU, Pitié-Salpêtrière Hospital, Paris, France

DOI: https://doi.org/10.3389/fpsyt.2021.685711
Journal volume & issue: Vol. 12

Abstract

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Autoimmune encephalitis (AIE) is a rare, severe, and rapidly progressive encephalopathy, and its diagnosis is challenging, especially in adolescent populations when the presentation is mainly psychiatric. Currently, cerebral 18-fluorodeoxyglucose positron emission tomography (18F-FDG-PET) imaging is not included in the diagnosis algorithm. We describe a 16-year-old patient with probable seronegative encephalitis with catatonia for which several cerebral PET scans were relevant and helpful for diagnosis, treatment decision making, and follow-up monitoring. The patient recovered after 2 years of treatment with etiologic treatment of AIE and treatment of catatonia. This case suggests a more systematic assessment of the clinical relevance of 18F-FDG-PET imaging in probable seronegative AIE.

Published in Frontiers in Psychiatry

ISSN: 1664-0640 (Online)
Publisher: Frontiers Media S.A.
Country of publisher: Switzerland
LCC subjects: Medicine: Internal medicine: Neurosciences. Biological psychiatry. Neuropsychiatry: Neurology. Diseases of the nervous system: Psychiatry
Website: https://www.frontiersin.org/journals/psychiatry

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