Indian Journal of Urology (Jan 2002)
Complicated nosocomial UTI caused by nonfermenters
Abstract
Aerobic nonfermenting gram-negative bacilli (nonfer-menters) usually considered as contaminants are emerg-ing as important nosocomial pathogens. 110 such strains obtained from 4200 consecutive urinary tract specimens were characterized by a battery of biochemical tests. Antibiotic susceptibility was tested against gentamicin, amikacin, netilmicin, ceftazidime, piperacillin and ciprof oxacin. Significance was assigned by taking into account clinical details and isolation of the same organ-ism in the repeat specimen. Pseudomonas spp. (45.5%) were the commonest followed by Acinetobacter spp. (39%), Alcaligenes spp. (8%) and Flavobacter spp. (3.63%). Two strains of Weeksella virosa, and one each of Xanthomonas rnaltophilia and CDCllg were also re-covered. Pseudomonas aeruginosa and Acinetobacter baumanii were the most common significant isolates (62.9% and 25.9% respectively). Alcaligenes spp. was found to be etiologically significant in 5 out of 7 cases. In only 2 cases (4%) isolation of a Pseudomonas spp other than Paeruginosa was considered significant. Out of 4 strains of Flavobacter spp. only one could be confirmed as significant. Postoperative period (42.6%) followed by obstructive uropathy (32%) and surgery on urinary tract (8%) were commonest risk factors. All strains except a few showed high level of drug resistance.
