Influence of thyrotropic herbal remedy on vascular endothelium and thyroid gland structure in experimental hypothyroidism

Abstract

The work presents evaluation of influence of plant preparation «Thyreoton-forte» on endothelium of vessels and morphological structure of thyroid gland in experimental hypothyreosis. Experimental hypothyreosis in rats was induced by administration of mercazolilum (10 mg/kg, intragastric introduction) during 28 days. The course administration of «Thyreoton-forte» (50,100 mg/kg, intragastric introduction) decreases the number of circulating endothelial cells (p < 0,05) and normalizes the structure of thyroid gland. Pharmacological effect of «Thyreoton-forte» is provided by protective influence in vascular endothelium and positive action on thyroid gland.

Keywords

• «тиреотон-форте»
• hypothyroidism
• «thyreoton-forte»
• endothelium
• thyroid gland